Reconstructing subcortical activities from high-density scalp EEG


April 2019

Seeber M., Michel C.

A number of serious diseases, i.e. Parkinson’s, Tourette syndrome and obsessive-compulsive disorders (OCD) are directly associated with subcortical regions. Deep brain stimulation (DBS) is applied as a therapy for severe cases suffering from these diseases. While subcortical areas are known to play an important role in mediating interactions in large-scale networks, it is less clear how their dysfunction affect certain diseases. Furthermore, it is an ongoing discussion how DBS influences subcortical-cortical networks dynamics leading to the treatment’s outcome. In order to study electrophysiological dynamics in subcortical regions, implanted electrodes in these areas are needed. This neurosurgery is naturally only justifiable and possible in the framework of deep brain stimulation therapy, which restricts investigating subcortical dynamics in humans to a few case studies.

Neuroadaptive Bayesian Optimization: a closed-loop approach for non-invasive brain stimulation


April 2019

Violante I.R., Leech R., Lorenz R.

Brain stimulation is an increasingly popular field, capturing the creativity of DIY brain hackers and neurotechnology enthusiasts. Among scientists and clinicians, non-invasive brain stimulation (NIBS) is seen as a tool to causally investigate brain-behaviour relations and a promising treatment for a variety of neurological and psychiatric disorders [1]. Here we introduce our novel approach, Neuroadaptive Bayesian Optimization, designed to tackle limitations associated with conventional applications of NIBS, and define individualised stimulation protocols to inform clinical applications with optimal efficacy.

BIO-X: Biocomplexity, Biodesign, Bioinnovation, Biomanufacturing and Bioentrepreneurship


December 2018

The 17th International Summer School on BIO-X: Biocomplexity, Biodesign, Bioinnovation, Biomanufacturing and Bioentrepreneurship, sponsored by the NSF, the University of Houston Biomedical Engineering Department and technically co-sponsored by the IEEE Brain Initiative and the IEEE Engineering in Medicine and Biology Society, was held at the Chania Academy, Crete, June 11-17, 2018. This summer school was a continuation of previous summer schools. Thirty students and six distinguished and three junior faculty (post-docs) attended the 17th summer school. The NSF, the IEEE Brain Initiative and the University of Houston co-sponsored 30 students. 

Listening to the Brain with Hearing Devices

Bleichner M. G., Grzybowski M., Ernst S. M. A. , Kollmeier B. , Debener S. , Denk F.

While you are reading this text, pay attention to the sounds around you. How many different sounds do you notice? Where do they come from? Concentrate on one of them. Is the sound high or low pitched? Now concentrate on a different sound. Does that sound have a specific rhythm?

Near-infrared Upconversion Optogenetics Helps Brain Stimulation Go Deep

Shuo Chen

For decades, scientists and physicians have electrically stimulated neurons deep in the brain with implanted electrodes connected through wires to a pacemaker-like device under the skin of the chest. This approach, known as deep brain stimulation (DBS), can treat patients with various neurological symptoms, such as Parkinson’s disease and major depression.

The Decoding of Oscillatory Brain Dynamics induced by Haptic Stimuli and Imagined Haptic Stimuli Sensation and its application for a Novel Type of Somatosensory Brain-computer Interface

Lin Yao, Ning Jiang.

Brain-computer Interface (BCI) permits a direct channel between the brain and the external environment, bypassing the physiological channel for such interaction, i.e. the neuromuscular system. This technology can be useful in medical applications, including locked-in syndrome, stroke, spinal cord injury, and cerebral palsy, as well as applications of a more general purpose such as education, ergonomics, and manufacturing. Event-related desynchronization (ERD) and synchronization (ERS) of brain signals and movement-related cortical potentials (MRCP), both of which are generated during motor imagery tasks (MI), have been shown to allow real-time, direct BCI control.

Meeting of the Global Current and Emerging Brain Initiatives at the IEEE SMC BMI Workshop

Michael H. Smith

On October 9, 2018, the SMC Brain-Machine Interface Systems (BMI) Workshop also featured a first-of-its-kind meeting of Global Current and Emerging Brain Initiatives. This meeting was hosted by the IEEE President, James Jefferies, and Chaired by Michael H. Smith. The meeting brought together global Brain Initiative leaders and representatives from other groups working on large-scale multi-year brain projects from Australia, Canada, China, Europe, Japan, Korea, New Zealand, Poland, Russia, and the US as well as representatives from the IEEE Brain Initiative, the International Neuroethics Society, industry, and other stakeholders.

Reminiscence of Seventh International BCI Meeting

Koji Koizumi

This was the first time I attended the International BCI meeting. This event took place on May 21 – 25, 2018 at the Asilomar Conference Center in Pacific Grove, California, USA. To tell the truth, this was the first conference I have attended. Just about the time I finished writing my graduation thesis at the University of Tokyo, I got to know about this meeting through the call for papers via its website. Because I was just beginning in BCI, I wanted to deepen my understanding of the field and benefit from the experience and advice of other researchers. Therefore, I immediately decided to submit an abstract. Fortunately, I received the Student Award at this meeting and received a travel grant from the IEEE Brain Initiative. I would like to take this opportunity to express my appreciation to IEEE Brain Initiative. In conclusion, this conference was truly amazing and I was really pleased having participated in this conference.

Discovery of New Neurological Networks

Dr. Salvatore Domenic Morgera

The human nervous system provides energy efficient, highly complex realization and control of how we sense, think and act. For machines designed by humans, the ideas of energy efficiency and complexity are at odds, thus the question of how the central nervous system (CNS) really works has received intense scrutiny for decades. Researchers at the University of South Florida (USF) under the direction of Dr. Sal Morgera have discovered a sophisticated electric near-field generated in an energy efficient, natural manner by our billions of myelinated nerve fibers. This electric near-field is roughly the counterpart of the magnetic near-field used in smartphone contactless payment services such as Apple Pay® and Google Wallet®, known as Near Field Communications, or NFC.

Capturing Touch for Prosthetic Limbs Through Artificial Skin

Luke E. Osborn and Nitish V. Thakor

Those living with upper limb differences face numerous challenges, including lost limb movement and dexterity as well as missing sensory information during object manipulation. From a user’s perspective, upper limb prostheses still have several issues with control, general discomfort from the socket, and lack of sensory feedback 1. Significant efforts have resulted in sophisticated algorithms for decoding intended prosthesis movements along multiple degrees of freedom that have enabled amputees to regain more dexterous prosthesis control 2. Another seminal advancement is targeted muscle reinnervation surgery 3, which targets nerves to different intact muscle groups such as on the chest to provide a source of well differentiated myoelectric signals for prosthesis control.

About BrainInsight

BrainInsight, the IEEE Brain Initiative eNewsletter, is a quarterly online publication, featuring practical and timely information and forward-looking commentary on neurotechnologies. BrainInsight describes recent breakthroughs in research, primers on methods of interests, or report recent events such as conferences or workshops.

Managing Editor

Ricardo Chavarriaga
Zurich University of Applied Science(ZHAW)
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