A Large-scale Standardized Physiological Pipeline Reveals Functional Organization of the Mouse Visual Cortex

Saskia de Vries

An important open question in visual neuroscience is how visual information is represented in the cortex. Important results characterized neural coding by assessing the responses to artificial stimuli, with the assumption that responses to gratings, for example, capture the key features of neural responses, and deviations, such as extra-classical effects, are relatively minor. The failure of these responses to have strong predictive power has renewed these questions. It has been suggested that this characterization of visual responses has been strongly influenced by the biases inherent in recording methods and the limited stimuli used in experiments.