Speech communication accounts for a significant amount of the social interactions in daily life. Neurological conditions like amyotrophic lateral sclerosis, stroke, brain tumor and traumatic brain injury can lead to the paralysis or impairment of the vocal structures responsible for speech production. For these patients, restoring speech functioning is one of the crucial components for their rehabilitation.

Adelson Chua and Rikky Muller Department of Electrical Engineering and Computer Sciences at the University of California, Berkeley Epilepsy affects about 50 million people worldwide and is characterized by recurring seizures that can lead to involuntary movements, loss of consciousness, and even death. Several technology-based solutions for monitoring and treating epilepsy have emerged in recent years involving wearable and implantable …

Monitoring large groups of neurons in various brain regions, including superficial and deep structures, is crucial for advancing neuroscience research on cognition, motor control, behavior, among other areas [1], [2]. Current extracellular CMOS high-density neural probes are becoming the new standard in electrophysiology, allowing for simultaneous recording with excellent spatial and temporal resolution [3]–[5]. However, there is still a demand for neural recording technologies that can access a significantly larger number of neurons, allowing for the decoding of more complex motor, sensory, and cognitive tasks. To achieve this, it is necessary to develop neural probes with much higher number of channels, which requires the design of readout circuits that meet several requirements, including: i) area- and power-efficiency, ii) low noise to capture weak neural signals, iii) capability to interface with large-impedance and high-DC-offset electrodes, and iv) tolerance to artifacts caused by movement or concurrent electrical stimulation.