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Brain Stimulation Therapy: The Past, Present, and Future of Treatment through Brain Stimulation

Brain stimulation therapy is one of the next major frontiers in medical science. These therapies have already shown great promise in the treatment of neurological and mental disorders from Parkinson’s disease to major clinical depression.  Yet brain stimulation therapies are likely still in their infancy; current and ongoing research of brain networks and corresponding treatments suggests that future therapies could …

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Brain–Machine Interface Projects

The brain is an incredible, complex organ. Every year researchers reveal new information on how the brain functions and how neural circuits operate. And each new discovery presents a new opportunity to make life easier for thousands or even millions of people.The emerging field of brain–machine interface (BMI), or brain–computer interface (BCI), is just one area of neuroscience that shows …

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Closed-Loop Neurotechnologies

Understanding the brain and other areas of the nervous system has always been challenging. While research has led to a better understanding at the cellular/neuron level, a clear picture of how those neurons work together as part of a larger system of neural circuits has been more evasive.  Closed-loop neurotechnologies, an expanding area of study, are advancing the reading and …

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Neurotherapy: Treating Disorders by Retraining the Brain

There still exists a number of psychiatric, neurologic, and other brain-related disorders without highly effective treatment. Could neurotherapy hold the key to treating such diseases? Neurotherapy, while still very early in its development, has already shown efficacy in altering brain function to provide relief to patients suffering from a range of disorders. This article will discuss the current state of …

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Neurotechnologies: The Next Technology Frontier

For millennia, the human brain has been a largely unexplored frontier. Relative to the whole of human history, studying, understanding, and influencing human thought and consciousness is a radically new endeavor. Only in the twenty-first century has science truly begun to progress far enough into the field of neuroscience for effective neurotechnologies to begin to take shape.  The implications of …

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Brain Machine Interfaces: Concept to Clinic

Over the last two decades neural prostheses that aim to restore lost motor function have moved quickly from concept to laboratory development and clinical demonstration. In parallel, advances in neural interfacing technologies poised to broaden clinical application of these prostheses are actively in development in both academic and industry settings.

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Optimizing Control and Learning in Neural Interfaces

Direct interfaces with the brain provide exciting new ways to restore and repair neurological function. For instance, motor Brain-Machine Interfaces (BMIs) can bypass a paralyzed person’s injury by repurposing intact portions of their brain to control movements. Recent work shows that BMIs do not simply “decode” subjects’ intentions—they create new systems subjects learn to control. To improve BMI performance and …

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A Large-scale Standardized Physiological Pipeline Reveals Functional Organization of the Mouse Visual Cortex

An important open question in visual neuroscience is how visual information is represented in the cortex. Important results characterized neural coding by assessing the responses to artificial stimuli, with the assumption that responses to gratings, for example, capture the key features of neural responses, and deviations, such as extra-classical effects, are relatively minor. The failure of these responses to have …